Setzole Lotion is an antifungal medicine. It kills and prevents the growth of fungus. This relieves the symptoms caused by the infection. It may be used to treat infections such as athleteÃ¢ÂÂs foot, Dhobie Itch, thrush, ringworm, and dry, flaky skin. You should keep using it for as long as it is prescribed even if your symptoms have gone. This will prevent the infection from coming back. Using this medicine as prescribed will relieve pain and itching and may help you feel more comfortable with your skin.