Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other parts of your body. Zayo 100 Tablet is a combination of two medicine namely valsartan and sacubitril. Both of these medicines work in different ways to lower blood pressure. This makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.